Our physical appearance conditions us toward society. Pieles is the story of physically different people who, for that very reason, have been forced into hiding, into becoming recluses or into joining together. Samantha (a woman whose digestive system is backward), Laura (a girl with no eyes) and Ana (a woman with a deformed face), are lovely characters struggling to find themselves in a society that only understands one physical form and that excludes and mistreats anyone different.